Dr Alice Cezanne
College Research Associate
SpecialisationMolecular Biology
Research interestsDr Alice Cezanne started her scientific career with a BSc. Hons. in Medical Sciences at the University of Edinburgh and a PhD in Biochemistry at the Max Planck Institute for Molecular Cell Biology and Genetics in Dresden, Germany. During her PhD she developed a passion for how membrane properties shape and regulate cellular processes. Having always been fascinated by astrobiology and the ability of living systems to survive a wide range of environments, she became interested in how cells can maintain a functional and dynamic membrane under extreme conditions.
As a post-doctoral researcher at the MRC Laboratory of Molecular Biology, Alice investigates how lipid membranes are physically and chemically remodelled during cell division in extremophile archaea. Despite dramatic differences in membrane lipids, cell division in some archaea is driven by homologues of the ESCRT-III complex, just as it is in many eukaryotes. Through investigation of how a conserved protein machinery can act on different membrane architectures, and how the membrane itself contributes to cytokinesis and abscission, Alice hopes to gain an understanding of principles that are fundamental to cell division as well as shed some light on the evolution of the comparatively more complex division machinery in eukaryotes.
As a post-doctoral researcher at the MRC Laboratory of Molecular Biology, Alice investigates how lipid membranes are physically and chemically remodelled during cell division in extremophile archaea. Despite dramatic differences in membrane lipids, cell division in some archaea is driven by homologues of the ESCRT-III complex, just as it is in many eukaryotes. Through investigation of how a conserved protein machinery can act on different membrane architectures, and how the membrane itself contributes to cytokinesis and abscission, Alice hopes to gain an understanding of principles that are fundamental to cell division as well as shed some light on the evolution of the comparatively more complex division machinery in eukaryotes.
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